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After an initial balance favoring collagen formation and mineralization, bone turnover markers return to pre-treatment levels during long-term TNF-α inhibition in patients with ankylosing spondylitis

BACKGROUND: Bone turnover balance favors bone formation, especially mineralization, during the first 3 years of treatment with TNF-α inhibitors (TNFi). Our aim was to evaluate the course of serum bone turnover markers (BTM) and to investigate if facilitation of mineralization reflected by BTM BALP c...

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Detalles Bibliográficos
Autores principales: Siderius, Mark, Spoorenberg, Anneke, Kroese, Frans G. M., van der Veer, Eveline, Arends, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038252/
https://www.ncbi.nlm.nih.gov/pubmed/36961859
http://dx.doi.org/10.1371/journal.pone.0283579