CTLA4, SH2B3, and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of Type 1 diabetes patients

The HLA region is the major genetic risk determinant of Type 1 diabetes. How non-HLA loci contribute to the genetic risk is incompletely understood, but there are indications that at least some impact progression of asymptomatic autoimmunity. We examined whether SNPs in 7 susceptibility loci (INS, S...

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Detalles Bibliográficos
Autores principales: Vandewalle, Julie, Desouter, Aster K, Van der Auwera, Bart J, Tenoutasse, Sylvie, Gillard, Pieter, De Block, Christophe, Keymeulen, Bart, Gorus, Frans K, Van de Casteele, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Autoimmunity / Autoimmune Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038324/
https://www.ncbi.nlm.nih.gov/pubmed/36622793
http://dx.doi.org/10.1093/cei/uxad002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038324/
https://www.ncbi.nlm.nih.gov/pubmed/36622793
http://dx.doi.org/10.1093/cei/uxad002

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