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The lactate dehydrogenase (LDH) isoenzyme spectrum enables optimally controlling T cell glycolysis and differentiation

Isoenzyme divergence is a prevalent mechanism governing tissue-specific and developmental stage-specific metabolism in mammals. The lactate dehydrogenase (LDH) isoenzyme spectrum reflects the tissue-specific metabolic status. We found that three tetrameric isoenzymes composed of LDHA and LDHB (LDH-3...

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Detalles Bibliográficos
Autores principales: Chen, Xuyong, Liu, Lingling, Kang, Siwen, Gnanaprakasam, JN Rashida, Wang, Ruoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038341/
https://www.ncbi.nlm.nih.gov/pubmed/36961904
http://dx.doi.org/10.1126/sciadv.add9554