Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines

Finding effective therapies against cancers driven by mutant and/or overexpressed hyperactive G-proteins remains an area of active research. Polyisoprenylated cysteinyl amide inhibitors (PCAIs) are agents that mimic the essential posttranslational modifications of G-proteins. It is hypothesized that...

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Detalles Bibliográficos
Autores principales: Tawfeeq, Nada, Lazarte, Jassy Mary S., Jin, Yonghao, Gregory, Matthew D., Lamango, Nazarius S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038354/
https://www.ncbi.nlm.nih.gov/pubmed/36961909
http://dx.doi.org/10.18632/oncotarget.28390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038354/
https://www.ncbi.nlm.nih.gov/pubmed/36961909
http://dx.doi.org/10.18632/oncotarget.28390

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