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Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel

Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive, but the mechanisms of mechanosensitivity remain po...

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Detalles Bibliográficos
Autores principales: Strege, Peter R, Cowan, Luke M, Alcaino, Constanza, Mazzone, Amelia, Ahern, Christopher A, Milescu, Lorin S, Farrugia, Gianrico, Beyder, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038658/
https://www.ncbi.nlm.nih.gov/pubmed/36912788
http://dx.doi.org/10.7554/eLife.79271