Baculovirus-expressed self-assembling SARS-CoV-2 nanoparticle vaccines targeting the S protein induce protective immunity in mice

Spike (S) protein, a homotrimeric glycoprotein, is the most important antigen target for SARS-CoV-2 vaccines. A complete simulation of the advanced structure of this homotrimer during subunit vaccine development is the most likely method to improve its immunoprotective effects. In this study, prepar...

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Detalles Bibliográficos
Autores principales: Liu, Xingjian, Song, Haozhi, Jiang, Jianmin, Gao, Xintao, Yi, Yongzhu, Shang, Yuting, Li, Jialei, Li, Dan, Zeng, Zhen, Li, Yinü, Zhang, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038678/
https://www.ncbi.nlm.nih.gov/pubmed/37007452
http://dx.doi.org/10.1016/j.procbio.2023.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038678/
https://www.ncbi.nlm.nih.gov/pubmed/37007452
http://dx.doi.org/10.1016/j.procbio.2023.03.026

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