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Baculovirus-expressed self-assembling SARS-CoV-2 nanoparticle vaccines targeting the S protein induce protective immunity in mice

Spike (S) protein, a homotrimeric glycoprotein, is the most important antigen target for SARS-CoV-2 vaccines. A complete simulation of the advanced structure of this homotrimer during subunit vaccine development is the most likely method to improve its immunoprotective effects. In this study, prepar...

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Detalles Bibliográficos
Autores principales:	Liu, Xingjian, Song, Haozhi, Jiang, Jianmin, Gao, Xintao, Yi, Yongzhu, Shang, Yuting, Li, Jialei, Li, Dan, Zeng, Zhen, Li, Yinü, Zhang, Zhifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038678/ https://www.ncbi.nlm.nih.gov/pubmed/37007452 http://dx.doi.org/10.1016/j.procbio.2023.03.026

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