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Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target

Extrachromosomal circular DNA (ecDNA) has gained renewed interest since its discovery more than half a century ago, emerging as critical driver of tumor evolution. ecDNA is highly prevalent in many types of cancers, including colorectal cancer (CRC), which is one of the most deadly cancers worldwide...

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Detalles Bibliográficos
Autores principales: Chen, Yinnan, Qiu, Quanpeng, She, Junjun, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038807/
https://www.ncbi.nlm.nih.gov/pubmed/36859558
http://dx.doi.org/10.1038/s41388-023-02640-7