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Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target
Extrachromosomal circular DNA (ecDNA) has gained renewed interest since its discovery more than half a century ago, emerging as critical driver of tumor evolution. ecDNA is highly prevalent in many types of cancers, including colorectal cancer (CRC), which is one of the most deadly cancers worldwide...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038807/ https://www.ncbi.nlm.nih.gov/pubmed/36859558 http://dx.doi.org/10.1038/s41388-023-02640-7 |