Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells

Type-2 diabetes (T2D) is characterised by a dysregulation of metabolism, including skeletal muscle insulin resistance, mitochondrial dysfunction, and oxidative stress. Reactive species, such as methylglyoxal (MGO) and 4-hydroxynonenal (4-HNE), positively associate with T2D disease severity and can d...

Descripción completa

Detalles Bibliográficos
Autores principales: Matthews, Joseph J., Turner, Mark D., Santos, Livia, Elliott-Sale, Kirsty J., Sale, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038967/
https://www.ncbi.nlm.nih.gov/pubmed/36637533
http://dx.doi.org/10.1007/s00726-022-03230-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038967/
https://www.ncbi.nlm.nih.gov/pubmed/36637533
http://dx.doi.org/10.1007/s00726-022-03230-9

Ejemplares similares