GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway

In the process of inflammatory activation, macrophages exhibit lipid metabolism disorders and accumulate lipid droplets. Kupffer cells (KCs) are the resident hepatic macrophage with critical defense functions in the pathogenesis of several types of liver disease. How dysregulated lipid metabolism co...

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Detalles Bibliográficos
Autores principales: Fan, Guoqiang, Li, Yanfei, Zong, Yibo, Suo, Xiaoyi, Jia, Yimin, Gao, Mingming, Yang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039030/
https://www.ncbi.nlm.nih.gov/pubmed/36964139
http://dx.doi.org/10.1038/s41419-023-05741-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039030/
https://www.ncbi.nlm.nih.gov/pubmed/36964139
http://dx.doi.org/10.1038/s41419-023-05741-z

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