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Phase separation of α-crystallin-GFP protein and its implication in cataract disease

Cataract, the leading cause of blindness worldwide, is caused by crystallin protein aggregation within the protected lens environment. Phase separation has been implicated as an important mechanism of protein aggregation diseases, such as neurodegeneration. Similarly, cataract has been proposed to b...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Zhu, Ya-Xi, Huang, Rui-Yan, Bai, Shao-Mei, Zheng, Yu-Xing, Zheng, Jian, Xia, Zhao-Xia, Wang, Yun-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039050/
https://www.ncbi.nlm.nih.gov/pubmed/36964267
http://dx.doi.org/10.1038/s41598-023-31845-9