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The 8-bromobaicalein inhibited the replication of dengue, and Zika viruses and targeted the dengue polymerase

Dengue and Zika viruses are mosquito-borne flaviviruses burdening millions every year with hemorrhagic fever and neurological symptoms. Baicalein was previously reported as a potential anti-flaviviral candidate and halogenation of flavones and flavanones potentiated their antiviral efficacies. Here,...

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Detalles Bibliográficos
Autores principales: Boonyasuppayakorn, Siwaporn, Saelee, Thanaphon, Huynh, Thao Nguyen Thanh, Hairani, Rita, Hengphasatporn, Kowit, Loeanurit, Naphat, Cao, Van, Vibulakhaophan, Vipanee, Siripitakpong, Panattida, Kaur, Parveen, Chu, Justin Jang Hann, Tunghirun, Chairat, Choksupmanee, Opas, Chimnaronk, Sarin, Shigeta, Yasuteru, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039358/
https://www.ncbi.nlm.nih.gov/pubmed/36966240
http://dx.doi.org/10.1038/s41598-023-32049-x