Adenosine 2 receptor regulates autophagy and apoptosis to alleviate ischemia reperfusion injury in type 2 diabetes via IRE-1 signaling

PURPOSE: This study aimed to determine the effect and mechanism of action of adenosine 2 receptor (A2R) activation on myocardial ischemia reperfusion injury (MIRI) under diabetic conditions. METHODS: MIRI type 2 diabetic rats and H9C2 cardiomyocytes were treated with A2R agonist and then subjected t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yacouba Moukeila, Mohamed Bassirou, Thokerunga, Erick, He, Feng, Bongolo, Christian Cedric, Xia, Yun, Wang, Fuyu, Gado, Adamou Foumakoye, Mamoudou, Hama, Khan, Shahzad, Ousseina, Bonkano, Ousmane, Hadjara Abdoulkarim, Diarra, Drissa, Ke, Jianjuan, Zhang, Zongze, Wang, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039586/
https://www.ncbi.nlm.nih.gov/pubmed/36964482
http://dx.doi.org/10.1186/s12872-023-03116-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039586/
https://www.ncbi.nlm.nih.gov/pubmed/36964482
http://dx.doi.org/10.1186/s12872-023-03116-y

Ejemplares similares