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Metagenomic next-generation sequencing versus traditional laboratory methods for the diagnosis of central nervous system opportunistic infections in HIV-infected Chinese adults

To evaluate clinical value of metagenomic next-generation sequencing (mNGS) in people living with HIV/AIDS (PLWHA) who had CNS disorders. Cerebrospinal fluid (CSF) samples from 48 PLWHA presenting with CNS disorders were sequenced using mNGS and compared with clinical conventional diagnostic methods...

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Detalles Bibliográficos
Autores principales: Deng, Liping, Li, Qian, Hu, Wenjia, Chen, Xiaoping, Chen, Tielong, Song, Shihui, Mo, Pingzheng, Zou, Shi, Zhang, Yongxi, Gao, Shicheng, Chen, Liangjun, Zhuang, Ke, Yang, Rongrong, Xiong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039683/
https://www.ncbi.nlm.nih.gov/pubmed/36966258
http://dx.doi.org/10.1038/s41598-023-31974-1