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ZNF582 overexpression restrains the progression of clear cell renal cell carcinoma by enhancing the binding of TJP2 and ERK2 and inhibiting ERK2 phosphorylation

Recent evidences have suggested that Zinc finger protein 582 (ZNF582) plays different important roles in various tumors, but its clinical role, biological function and regulatory mechanism in clear cell renal cell carcinoma (ccRCC) are still vague. Through analyzing GEO and TCGA-KIRC data and valida...

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Detalles Bibliográficos
Autores principales: Yang, Wuping, Zhang, Zedan, Li, Lei, Zhang, Kenan, Xu, Yawei, Xia, Mancheng, Zhou, Jingcheng, Gong, Yanqing, Chen, Jinchao, Gong, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039855/
https://www.ncbi.nlm.nih.gov/pubmed/36966163
http://dx.doi.org/10.1038/s41419-023-05750-y