Synthesis and biological evaluation of substituted acetamide derivatives as potential butyrylcholinestrase inhibitors

Alzheimer’s disease (AD) is the most common type of age-related dementia. Inhibition of butyrylcholinesterase (BChE) emerge as an effective therapeutic target for AD. A series of new substituted acetamide derivatives were designed, synthesized and evaluated for their ability to inhibit BChE. The bio...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Dehong, Yang, Can, Liu, Yi, Lu, Tao, Li, Lizi, Chen, Gang, Liu, Zerong, Li, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039877/
https://www.ncbi.nlm.nih.gov/pubmed/36966194
http://dx.doi.org/10.1038/s41598-023-31849-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039877/
https://www.ncbi.nlm.nih.gov/pubmed/36966194
http://dx.doi.org/10.1038/s41598-023-31849-5

Ejemplares similares