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Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis
Synucleinopathies are neurodegenerative diseases characterized by pathological inclusions called “Lewy pathology” (LP) that consist of aggregated alpha-synuclein predominantly phosphorylated at serine 129 (PSER129). Despite the importance for understanding disease, little is known about the endogeno...
Autores principales: | Killinger, Bryan A., Mercado, Gabriela, Choi, Solji, Tittle, Tyler, Chu, Yaping, Brundin, Patrik, Kordower, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039879/ https://www.ncbi.nlm.nih.gov/pubmed/36966145 http://dx.doi.org/10.1038/s41531-023-00491-3 |
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