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The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics
The proliferation and differentiation of hepatic progenitor cells (HPCs) drive the homeostatic renewal of the liver under diverse conditions. Liver regeneration is associated with an increase in Axin2(+)Cnr1(+) HPCs, along with a marked increase in the levels of the endocannabinoid anandamide (AEA)....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039889/ https://www.ncbi.nlm.nih.gov/pubmed/36966147 http://dx.doi.org/10.1038/s41420-023-01400-6 |