The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics

The proliferation and differentiation of hepatic progenitor cells (HPCs) drive the homeostatic renewal of the liver under diverse conditions. Liver regeneration is associated with an increase in Axin2(+)Cnr1(+) HPCs, along with a marked increase in the levels of the endocannabinoid anandamide (AEA)....

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Bani, Holovac, Kellie, Schuebel, Kornel, Mukhopadhyay, Partha, Cinar, Resat, Iyer, Sindhu, Marietta, Cheryl, Goldman, David, Kunos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039889/
https://www.ncbi.nlm.nih.gov/pubmed/36966147
http://dx.doi.org/10.1038/s41420-023-01400-6

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