Cargando…

Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes

Deubiquitinating enzymes are key regulators in the ubiquitin system and an emerging class of drug targets. These proteases disassemble polyubiquitin chains and many deubiquitinases show selectivity for specific polyubiquitin linkages. However, most biochemical insights originate from studies of sing...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Tol, Bianca D. M., van Doodewaerd, Bjorn R., Lageveen-Kammeijer, Guinevere S. M., Jansen, Bas C., Talavera Ormeño, Cami M. P., Hekking, Paul J. M., Sapmaz, Aysegul, Kim, Robbert Q., Moutsiopoulou, Angeliki, Komander, David, Wuhrer, Manfred, van der Heden van Noort, Gerbrand J., Ovaa, Huib, Geurink, Paul P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039891/ https://www.ncbi.nlm.nih.gov/pubmed/36966155 http://dx.doi.org/10.1038/s41467-023-37363-6

Ejemplares similares

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets
por: Flierman, Dennis, et al.
Publicado: (2016)

Development of Diubiquitin‐Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes
por: Geurink, Paul P., et al.
Publicado: (2016)

Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases
por: Witting, Katharina F., et al.
Publicado: (2018)

Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor
por: Hameed, Dharjath S., et al.
Publicado: (2022)

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease
por: Békés, Miklós, et al.
Publicado: (2016)

Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer
por: van der Heden van Noort, Gerbrand J., et al.
Publicado: (2017)

How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling
por: van der Heden van Noort, Gerbrand J., et al.
Publicado: (2018)

A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
por: Weber, Aurelia, et al.
Publicado: (2017)

Profiling DUBs and Ubl-specific proteases with activity-based probes
por: Geurink, Paul P., et al.
Publicado: (2019)

Total Chemical Synthesis of a Functionalized GFP Nanobody
por: Huppelschoten, Yara, et al.
Publicado: (2022)

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System
por: Janssen, Guido V., et al.
Publicado: (2021)

High sensitivity glycomics in biomedicine
por: Lageveen‐Kammeijer, Guinevere S. M., et al.
Publicado: (2021)

Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin**
por: El Oualid, Farid, et al.
Publicado: (2010)

Software-Assisted Data Processing Workflow for Intact Glycoprotein Mass Spectrometry
por: Moran, Alan B., et al.
Publicado: (2023)

Dopant-Enriched Nitrogen Gas for Enhanced Electrospray Ionization of Released Glycans in Negative Ion Mode
por: Madunić, Katarina, et al.
Publicado: (2021)

Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
por: Blöchl, Constantin, et al.
Publicado: (2023)

An Integrated Glycosylation Signature of Rheumatoid Arthritis
por: Mayboroda, Oleg A., et al.
Publicado: (2023)

In‐Plate Chemical Synthesis of Isopeptide‐Linked SUMOylated Peptide Fluorescence Polarization Reagents for High‐Throughput Screening of SENP Preferences
por: Huppelschoten, Yara, et al.
Publicado: (2022)

A Native Chemical Ligation Handle that Enables the Synthesis of Advanced Activity-Based Probes: Diubiquitin as a Case Study
por: Mulder, Monique P C, et al.
Publicado: (2014)

Diubiquitin-Based NMR Analysis: Interactions Between Lys6-Linked diUb and UBA Domain of UBXN1
por: Shahul Hameed, Dharjath, et al.
Publicado: (2020)

Total Chemical Synthesis of LC3A and LC3B Activity-Based Probes
por: Huppelschoten, Yara, et al.
Publicado: (2023)

N-Glycan Isomer Differentiation by Zero Flow Capillary Electrophoresis Coupled to Mass Spectrometry
por: Wagt, Sander, et al.
Publicado: (2022)

Sialic Acid Derivatization of Fluorescently Labeled N-Glycans Allows Linkage Differentiation by Reversed-Phase Liquid Chromatography–Fluorescence Detection–Mass Spectrometry
por: Moran, Alan B., et al.
Publicado: (2022)

High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype
por: Wang, Di, et al.
Publicado: (2022)

Chemical Tools to Study Protein ADP-Ribosylation
por: van der Heden van Noort, Gerbrand J.
Publicado: (2020)

Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes‐1 negatively regulates human neutrophils
por: Rumpret, Matevž, et al.
Publicado: (2021)

Integrated N- and O-Glycomics of Acute Myeloid Leukemia (AML) Cell Lines
por: Blöchl, Constantin, et al.
Publicado: (2021)

High-Throughput Glycomic Methods
por: Trbojević-Akmačić, Irena, et al.
Publicado: (2022)

In-Depth Analysis of the N-Glycome of Colorectal Cancer Cell Lines
por: Wang, Di, et al.
Publicado: (2023)

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection
por: Shin, Donghyuk, et al.
Publicado: (2020)

Synthesis of Stable NAD(+) Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC
por: Madern, Jerre M., et al.
Publicado: (2020)

Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput
por: Jia, Yuqing, et al.
Publicado: (2022)

Site-Specific N-Linked Glycosylation Analysis of Human Carcinoembryonic Antigen by Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry
por: Pont, Laura, et al.
Publicado: (2021)

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection
por: Kim, Robbert Q., et al.
Publicado: (2020)

BAP1/ASXL1 recruitment and activation for H2A deubiquitination
por: Sahtoe, Danny D., et al.
Publicado: (2016)

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples
por: Lageveen-Kammeijer, Guinevere S. M., et al.
Publicado: (2019)

Nedd8 hydrolysis by UCH proteases in Plasmodium parasites
por: Karpiyevich, Maryia, et al.
Publicado: (2019)

Specific (sialyl-)Lewis core 2 O-glycans differentiate colorectal cancer from healthy colon epithelium
por: Madunić, Katarina, et al.
Publicado: (2022)

Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos
por: Kooij, Raymond, et al.
Publicado: (2020)

Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype
por: Madunić, Katarina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9gaufekpdhv1lfh68s4pvu5655