DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease

Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and postmortem PD patients underlined increasing levels of the dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL), wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Masato, Anna, Plotegher, Nicoletta, Terrin, Francesca, Sandre, Michele, Faustini, Gaia, Thor, Andrea, Adams, Stephen, Berti, Giulia, Cogo, Susanna, De Lazzari, Federica, Fontana, Camilla Maria, Martinez, Paul Anthony, Strong, Randy, Bandopadhyay, Rina, Bisaglia, Marco, Bellucci, Arianna, Greggio, Elisa, Dalla Valle, Luisa, Boassa, Daniela, Bubacco, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039907/
https://www.ncbi.nlm.nih.gov/pubmed/36966140
http://dx.doi.org/10.1038/s41531-023-00485-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039907/
https://www.ncbi.nlm.nih.gov/pubmed/36966140
http://dx.doi.org/10.1038/s41531-023-00485-1

Ejemplares similares