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DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease
Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and postmortem PD patients underlined increasing levels of the dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL), wh...
Autores principales: | Masato, Anna, Plotegher, Nicoletta, Terrin, Francesca, Sandre, Michele, Faustini, Gaia, Thor, Andrea, Adams, Stephen, Berti, Giulia, Cogo, Susanna, De Lazzari, Federica, Fontana, Camilla Maria, Martinez, Paul Anthony, Strong, Randy, Bandopadhyay, Rina, Bisaglia, Marco, Bellucci, Arianna, Greggio, Elisa, Dalla Valle, Luisa, Boassa, Daniela, Bubacco, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039907/ https://www.ncbi.nlm.nih.gov/pubmed/36966140 http://dx.doi.org/10.1038/s41531-023-00485-1 |
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