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Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond

A long-term objective of network medicine is to replace our current, mainly phenotype-based disease definitions by subtypes of health conditions corresponding to distinct pathomechanisms. For this, molecular and health data are modeled as networks and are mined for pathomechanisms. However, many suc...

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Detalles Bibliográficos
Autores principales: Sadegh, Sepideh, Skelton, James, Anastasi, Elisa, Maier, Andreas, Adamowicz, Klaudia, Möller, Anna, Kriege, Nils M., Kronberg, Jaanika, Haller, Toomas, Kacprowski, Tim, Wipat, Anil, Baumbach, Jan, Blumenthal, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039912/
https://www.ncbi.nlm.nih.gov/pubmed/36966134
http://dx.doi.org/10.1038/s41467-023-37349-4