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An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer’s disease
Alzheimer’s disease (AD) predominantly occurs as a late onset (LOAD) form involving neurodegeneration and cognitive decline with progressive memory loss. Risk factors that include aging promote accumulation of AD pathologies, such as amyloid-beta and tau aggregates, as well as inflammation and oxida...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039917/ https://www.ncbi.nlm.nih.gov/pubmed/36966157 http://dx.doi.org/10.1038/s41467-023-37304-3 |