The oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism

The EWSR1::CREM fusion gene, caused by a chromosomal translocation t(10;22)(p11;q12), has been discovered in divergent malignancies, ranging from low-grade to highly malignant cancers. The translocation gives rise to a chimeric protein, EWSR1::CREM. The molecular mechanisms behind the oncogenic prop...

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Detalles Bibliográficos
Autores principales: Kaprio, Heidi, Siddiqui, Arafat, Saustila, Lotta, Heuser, Vanina D., Gardberg, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039922/
https://www.ncbi.nlm.nih.gov/pubmed/36966162
http://dx.doi.org/10.1038/s41598-023-31576-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039922/
https://www.ncbi.nlm.nih.gov/pubmed/36966162
http://dx.doi.org/10.1038/s41598-023-31576-x

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