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Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics

AMPA glutamate receptors (AMPARs) mediate excitatory neurotransmission throughout the brain. Their signalling is uniquely diversified by brain region-specific auxiliary subunits, providing an opportunity for the development of selective therapeutics. AMPARs associated with TARP γ8 are enriched in th...

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Detalles Bibliográficos
Autores principales: Zhang, Danyang, Lape, Remigijus, Shaikh, Saher A., Kohegyi, Bianka K., Watson, Jake F., Cais, Ondrej, Nakagawa, Terunaga, Greger, Ingo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039940/
https://www.ncbi.nlm.nih.gov/pubmed/36966141
http://dx.doi.org/10.1038/s41467-023-37259-5