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IKKα promotes lung adenocarcinoma growth through ERK signaling activation via DARPP-32-mediated inhibition of PP1 activity

Non-small cell lung cancer (NSCLC) accounts for 80–85% cases of lung cancer cases. Diagnosis at advanced stages is common, after which therapy-refractory disease progression frequently occurs. Therefore, a better understanding of the molecular mechanisms that control NSCLC progression is necessary t...

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Detalles Bibliográficos
Autores principales: Alam, Sk. Kayum, Wang, Li, Zhu, Zhu, Hoeppner, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039943/
https://www.ncbi.nlm.nih.gov/pubmed/36966223
http://dx.doi.org/10.1038/s41698-023-00370-3