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Targeted DNA demethylation of the ZNF334 promoter inhibits colorectal cancer growth

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Aberrant regulation of DNA methylation in promoters of tumor suppressor genes or proto-oncogenes is one of the fundamental processes driving the initiation and progression of CRC. Zinc-finger proteins (ZNFs) are one of the most a...

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Detalles Bibliográficos
Autores principales: Yang, Bin, Tang, Haiyu, Wang, Nan, Gu, Jian, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039945/
https://www.ncbi.nlm.nih.gov/pubmed/36966142
http://dx.doi.org/10.1038/s41419-023-05743-x