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Clinical trial on the efficacy and safety of NPC-15 for patients with xeroderma pigmentosum exaggerated sunburn reaction type: XP-1 study protocol for a multicentre, double-blinded, placebo-controlled, two-group crossover study followed by a long-term open study in Japan

INTRODUCTION: Xeroderma pigmentosum (XP) is a rare intractable disease without a fundamental treatment, presenting with severe photosensitivity, freckle-like pigmented and depigmented maculae and numerous skin cancers before the age of 10 years without strict sun protection. About 70% of the patient...

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Detalles Bibliográficos
Autores principales: Tsujimoto, Mariko, Kakei, Yasumasa, Yamano, Nozomi, Fujita, Takeshi, Ueda, Takehiro, Ono, Ryusuke, Murakami, Sae, Moriwaki, Shinichi, Nishigori, Chikako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040004/
https://www.ncbi.nlm.nih.gov/pubmed/36948554
http://dx.doi.org/10.1136/bmjopen-2022-068112