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Clinical trial on the efficacy and safety of NPC-15 for patients with xeroderma pigmentosum exaggerated sunburn reaction type: XP-1 study protocol for a multicentre, double-blinded, placebo-controlled, two-group crossover study followed by a long-term open study in Japan
INTRODUCTION: Xeroderma pigmentosum (XP) is a rare intractable disease without a fundamental treatment, presenting with severe photosensitivity, freckle-like pigmented and depigmented maculae and numerous skin cancers before the age of 10 years without strict sun protection. About 70% of the patient...
Autores principales: | Tsujimoto, Mariko, Kakei, Yasumasa, Yamano, Nozomi, Fujita, Takeshi, Ueda, Takehiro, Ono, Ryusuke, Murakami, Sae, Moriwaki, Shinichi, Nishigori, Chikako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040004/ https://www.ncbi.nlm.nih.gov/pubmed/36948554 http://dx.doi.org/10.1136/bmjopen-2022-068112 |
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