Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

BACKGROUND: Circulating transforming growth factor-β (TGF-β)-specific T cells that recognize TGF-β-expressing immune regulatory cells have been described in patients with cancer. TGF-β-derived peptide vaccination modulates the tumor microenvironment and has shown clinical effects in animal models of...

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Detalles Bibliográficos
Autores principales: Mortensen, Rasmus Erik Johansson, Holmström, Morten Orebo, Lisle, Thomas Landkildehus, Hasselby, Jane P, Willemoe, Gro L, Met, Özcan, Marie Svane, Inge, Johansen, Julia, Nielsen, Dorte L, Chen, Inna M, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040073/
https://www.ncbi.nlm.nih.gov/pubmed/36948507
http://dx.doi.org/10.1136/jitc-2022-006432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040073/
https://www.ncbi.nlm.nih.gov/pubmed/36948507
http://dx.doi.org/10.1136/jitc-2022-006432

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