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ceRNA network construction and identification of hub genes as novel therapeutic targets for age-related cataracts using bioinformatics

BACKGROUND: The aim of this study is to investigate the genetic and epigenetic mechanisms involved in the pathogenesis of age-related cataract (ARC). METHODS: We obtained the transcriptome datafile of th ree ARC samples and three healthy, age-matched samples and used differential expression analyses...

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Detalles Bibliográficos
Autores principales: Hong, Yingying, Wu, Jiawen, Sun, Yang, Zhang, Shenghai, Lu, Yi, Ji, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040182/
https://www.ncbi.nlm.nih.gov/pubmed/36987450
http://dx.doi.org/10.7717/peerj.15054