Nucleoporins facilitate ORC loading onto chromatin

The origin recognition complex (ORC) binds throughout the genome to initiate DNA replication. In metazoans, it is still unclear how ORC is targeted to specific loci to facilitate helicase loading and replication initiation. Here, we perform immunoprecipitations coupled with mass spectrometry for ORC...

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Detalles Bibliográficos
Autores principales: Richards, Logan, Lord, Christopher L., Benton, Mary Lauren, Capra, John A., Nordman, Jared T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040217/
https://www.ncbi.nlm.nih.gov/pubmed/36351393
http://dx.doi.org/10.1016/j.celrep.2022.111590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040217/
https://www.ncbi.nlm.nih.gov/pubmed/36351393
http://dx.doi.org/10.1016/j.celrep.2022.111590

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