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Cerebral organoids in primary progressive multiple sclerosis reveal stem cell and oligodendrocyte differentiation defect

Multiple sclerosis (MS) is an auto-immune inflammatory disorder affecting the central nervous system. The cause of the disease is unknown but both genetic and environmental factors are implicated in the pathogenesis. We derived cerebral organoids from induced pluripotent stem cells (iPSC) of healthy...

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Detalles Bibliográficos
Autores principales: Daviaud, Nicolas, Chen, Eric, Edwards, Tara, Sadiq, Saud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040243/
https://www.ncbi.nlm.nih.gov/pubmed/36744877
http://dx.doi.org/10.1242/bio.059845