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Translating non-coding genetic associations into a better understanding of immune-mediated disease

Genome-wide association studies have identified hundreds of genetic loci that are associated with immune-mediated diseases. Most disease-associated variants are non-coding, and a large proportion of these variants lie within enhancers. As a result, there is a pressing need to understand how common g...

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Detalles Bibliográficos
Autores principales: Stankey, Christina T., Lee, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040244/
https://www.ncbi.nlm.nih.gov/pubmed/36897113
http://dx.doi.org/10.1242/dmm.049790