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Translating non-coding genetic associations into a better understanding of immune-mediated disease
Genome-wide association studies have identified hundreds of genetic loci that are associated with immune-mediated diseases. Most disease-associated variants are non-coding, and a large proportion of these variants lie within enhancers. As a result, there is a pressing need to understand how common g...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040244/ https://www.ncbi.nlm.nih.gov/pubmed/36897113 http://dx.doi.org/10.1242/dmm.049790 |