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Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases
Prioritization of disease mechanisms, biomarkers, and drug targets in immune-mediated inflammatory diseases (IMIDs) is complicated by altered interactions between thousands of genes. Our multi-organ single-cell RNA sequencing of a mouse IMID model, namely collagen-induced arthritis, shows highly com...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040389/ https://www.ncbi.nlm.nih.gov/pubmed/36858042 http://dx.doi.org/10.1016/j.xcrm.2023.100956 |