Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases

Prioritization of disease mechanisms, biomarkers, and drug targets in immune-mediated inflammatory diseases (IMIDs) is complicated by altered interactions between thousands of genes. Our multi-organ single-cell RNA sequencing of a mouse IMID model, namely collagen-induced arthritis, shows highly com...

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Detalles Bibliográficos
Autores principales: Lilja, Sandra, Li, Xinxiu, Smelik, Martin, Lee, Eun Jung, Loscalzo, Joseph, Marthanda, Pratheek Bellur, Hu, Lang, Magnusson, Mattias, Sysoev, Oleg, Zhang, Huan, Zhao, Yelin, Sjöwall, Christopher, Gawel, Danuta, Wang, Hui, Benson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040389/
https://www.ncbi.nlm.nih.gov/pubmed/36858042
http://dx.doi.org/10.1016/j.xcrm.2023.100956

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