The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots

In mammals, meiotic recombination is initiated by the introduction of DNA double strand breaks (DSBs) into narrow segments of the genome, defined as hotspots, which is carried out by the SPO11/TOPOVIBL complex. A major player in the specification of hotspots is PRDM9, a histone methyltransferase tha...

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Detalles Bibliográficos
Autores principales: Giannattasio, Teresa, Testa, Erika, Palombo, Ramona, Chellini, Lidia, Franceschini, Flavia, Crevenna, Álvaro, Petkov, Petko M., Paronetto, Maria Paola, Barchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040399/
https://www.ncbi.nlm.nih.gov/pubmed/36967403
http://dx.doi.org/10.1007/s00018-023-04744-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040399/
https://www.ncbi.nlm.nih.gov/pubmed/36967403
http://dx.doi.org/10.1007/s00018-023-04744-5

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