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Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel disease

INTRODUCTION: Plasma neurofilament light chain (NfL) is a potential biomarker for neurodegeneration in Alzheimer's disease (AD), ischemic stroke, and non‐dementia cohorts with cerebral small vessel disease (CSVD). However, studies of AD in populations with high prevalence of concomitant CSVD to...

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Detalles Bibliográficos
Autores principales: Chong, Joyce R., Hilal, Saima, Ashton, Nicholas J., Karikari, Thomas K., Reilhac, Anthonin, Vrooman, Henri, Schöll, Michael, Zetterberg, Henrik, Blennow, Kaj, Chen, Christopher P., Lai, Mitchell K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040495/
https://www.ncbi.nlm.nih.gov/pubmed/36994314
http://dx.doi.org/10.1002/dad2.12396