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KW2449 ameliorates collagen-induced arthritis by inhibiting RIPK1-dependent necroptosis

OBJECTIVE: Necroptosis has recently been found to be associated with the pathogenesis of many autoimmune diseases, including rheumatoid arthritis (RA). This study was undertaken to explore the role of RIPK1-dependent necroptosis in the pathogenesis of RA and the potential new treatment options. METH...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Ye, Qinbin, Xi, Xiaoyu, Cao, Xiaoxue, Wang, Xing, Zhang, Mengxiao, Xu, Yuan, Deng, Tingting, Deng, Xiaobing, Zhang, Guoqiang, Xiao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040599/
https://www.ncbi.nlm.nih.gov/pubmed/36993980
http://dx.doi.org/10.3389/fimmu.2023.1135014