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Population pharmacokinetics of tigecycline in critically ill patients

Objective: In critically ill patients, the change of pathophysiological status may affect the pharmacokinetic (PK) process of drugs. The purpose of this study was to develop a PK model for tigecycline in critically ill patients, identify the factors influencing the PK and optimiz dosing regimens. Me...

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Detalles Bibliográficos
Autores principales: Luo, Xiangru, Wang, Shiyi, Li, Dong, Wen, Jun, Sun, Na, Fan, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040605/
https://www.ncbi.nlm.nih.gov/pubmed/36992827
http://dx.doi.org/10.3389/fphar.2023.1083464