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N(6)-Methyladenosine Methyltransferase METTL3 Alleviates Diabetes-Induced Testicular Damage through Modulating TUG1/Clusterin Axis

BACKGROUND: The present study investigated the regulatory effects of N(6)-methyladenosine (m6A) methyltransferase like-3 (METTL3) in diabetes-induced testicular damage. METHODS: In vivo diabetic mice and high glucose (HG) treated GC-1 spg cells were established. The mRNA and protein expressions were...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Xiao, Yue-Hai, Sun, Chao, Liu, Bei, Sun, Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040629/
https://www.ncbi.nlm.nih.gov/pubmed/36653890
http://dx.doi.org/10.4093/dmj.2021.0306