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Improvement of loperamide-hydrochloride-induced intestinal motility disturbance by Platycodon grandiflorum polysaccharides through effects on gut microbes and colonic serotonin

Constipation is a common gastrointestinal symptom characterized by intestinal motility disorder. The effects of Platycodon grandiflorum polysaccharides (PGP) on intestinal motility have not been confirmed. We established a rat model of constipation induced by loperamide hydrochloride to elucidate th...

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Detalles Bibliográficos
Autores principales: Hao, Mengqi, Song, Jing, Zhai, Xiaohu, Cheng, Nuo, Xu, Cong, Gui, Shuangying, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040651/
https://www.ncbi.nlm.nih.gov/pubmed/36992686
http://dx.doi.org/10.3389/fcimb.2023.1105272