Destabilization of microrchidia family CW‐type zinc finger 2 via the cyclin‐dependent kinase 1‐chaperone‐mediated autophagy pathway promotes mitotic arrest and enhances cancer cellular sensitivity to microtubule‐targeting agents

BACKGROUND: Microtubule‐targeing agents (MTAs), such as paclitaxel (PTX) and vincristine (VCR), kill cancer cells through activtion of the spindle assembly checkpoint (SAC) and induction of mitotic arrest, but the development of resistance poses significant clinical challenges. METHODS: Immunoblotti...

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Detalles Bibliográficos
Autores principales: Hu, Shu‐Yuan, Qian, Jin‐Xian, Yang, Shao‐Ying, Andriani, Lisa, Liao, Li, Deng, Ling, Huang, Min‐Ying, Zhang, Yin‐Ling, Zhang, Fang‐Lin, Shao, Zhi‐Min, Li, Da‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040724/
https://www.ncbi.nlm.nih.gov/pubmed/36967563
http://dx.doi.org/10.1002/ctm2.1210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040724/
https://www.ncbi.nlm.nih.gov/pubmed/36967563
http://dx.doi.org/10.1002/ctm2.1210

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