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Alterations in oligodendrocyte transcriptional networks reveal region-specific vulnerabilities to neurological disease

Neurological disease is characterized the by dysfunction of specific neuroanatomical regions. To determine whether region-specific vulnerabilities have a transcriptional basis at cell-type-specific resolution, we analyzed gene expression in mouse oligodendrocytes across various brain regions. Oligod...

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Detalles Bibliográficos
Autores principales: Tommasini, Dario, Fox, Rachel, Ngo, Kathie J., Hinman, Jason D., Fogel, Brent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040735/
https://www.ncbi.nlm.nih.gov/pubmed/36994077
http://dx.doi.org/10.1016/j.isci.2023.106358