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Cortex-specific transcriptome profiling reveals upregulation of interferon-regulated genes after deeper cerebral hypoperfusion in mice

Background: Chronic cerebral hypoperfusion (CCH) is commonly accompanied by brain injury and glial activation. In addition to white matter lesions, the intensity of CCH greatly affects the degree of gray matter damage. However, little is understood about the underlying molecular mechanisms related t...

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Detalles Bibliográficos
Autores principales: Zhang, Zengyu, Guo, Zimin, Tu, Zhilan, Yang, Hualan, Li, Chao, Hu, Mengting, Zhang, Yuan, Jin, Pengpeng, Hou, Shuangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040763/
https://www.ncbi.nlm.nih.gov/pubmed/36994418
http://dx.doi.org/10.3389/fphys.2023.1056354