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A low-protein maternal diet during gestation affects the expression of key pancreatic β-cell genes and the methylation status of the regulatory region of the MafA gene in the offspring of Wistar rats

Maternal nutrition during gestation has important effects on gene expression-mediated metabolic programming in offspring. To evaluate the effect of a protein-restricted maternal diet during gestation, pancreatic islets from male progeny of Wistar rats were studied at postnatal days (PND) 36 (juvenil...

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Detalles Bibliográficos
Autores principales: Sosa-Larios, Tonantzin C., Ortega-Márquez, Ana L., Rodríguez-Aguilera, Jesús R., Vázquez-Martínez, Edgar R., Domínguez-López, Aaron, Morimoto, Sumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040775/
https://www.ncbi.nlm.nih.gov/pubmed/36992977
http://dx.doi.org/10.3389/fvets.2023.1138564