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The signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet β cells in response to high glucose

Glucose-stimulated insulin secretion of pancreatic β cells is essential in maintaining glucose homeostasis. Recent evidence suggests that the Nephrin-mediated intercellular junction between β cells is implicated in the regulation of insulin secretion. However, the underlying mechanisms are only part...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Yuan, Ying-Chao, Chang, Cong, Izumi, Tetsuro, Wang, Hong-Hui, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040812/
https://www.ncbi.nlm.nih.gov/pubmed/36822326
http://dx.doi.org/10.1016/j.jbc.2023.103045